Strengthening the liver: Natural support for histamine intolerance

The liver is one of the most important metabolic organs in our body. It is our largest detoxification organ and storage site for essential nutrients that ensure our bodily functions can be maintained. Every day, about 200 liters of blood flow through the liver. Furthermore, it filters out waste products, pathogens, medications, and alcohol, which are then excreted via the bile and kidneys.

An overloaded liver can lead to a multitude of ailments and even promote the development of histamine intolerance. In this article, you will learn how to support and relieve your liver in a natural way to improve your health and well-being. We will show you the causes and symptoms of liver overload, the role it plays in histamine intolerance, and the simple measures you can take to strengthen your liver and bring it back into balance. Read on to learn more!

The liver as a key organ in histamine metabolism: Tasks and functions

Our liver is primarily responsible for the detoxification of toxins, heavy metals, and medications. It produces bile and processes carbohydrates, fats, and proteins. The liver also stores energy sources (glycogen and fats), vitamins, and micronutrients. Furthermore, the liver is involved in the formation of important blood-clotting components and blood proteins. Another often underestimated but essential primary task is the breakdown of hormones, such as estrogen.

Connection between liver function and histamine intolerance

And what exactly does an overloaded liver have to do with histamine intolerance? There are two enzymes responsible for breaking down histamine in the body:

1. Diamine oxidase (DAO), which is active in the gut, tissue, and blood
2. Histamine N-methyltransferase (HNMT), which is located in the liver, bronchial mucosa, and central nervous system (CNS)

An overloaded and sluggish liver is therefore also considered one of the possible causes of histamine intolerance. Because if the liver is overloaded—for example, due to heavy metal exposure, improper diet, or stress—

• The enzyme activity of HNMT can be impaired
• A nutrient deficiency can develop, which may promote histamine intolerance
• Detoxification processes can be disrupted or take place inadequately, which can promote or worsen heavy metal accumulation. This can, for instance, also foster the development of histamine intolerance.
• A reactivated Epstein-Barr virus can attach itself and further burden the liver.

Histamine-related symptoms are mainly caused by a deficiency of the histamine-degrading enzyme diamine oxidase (DAO). However, a reduction in the activity of the second histamine-degrading enzyme, histamine N-methyltransferase (HNMT), can intensify the symptoms. The normal function of HNMT can be impaired due to genetics or environmental influences. While symptoms of a DAO deficiency often occur in bouts and usually immediately after a histamine-rich meal, they can also occur with a time delay in the case of an HNMT deficiency, with the brain, bronchial mucosa, and liver being particularly affected, as described above.

Understanding liver overload: Causes, symptoms, and diagnostics

Various factors can promote or cause liver overload. This includes not only excessive consumption of alcohol and nicotine. The complaints of an overloaded organ can be very individual and may not directly indicate that a liver overload is present.

Causes of an overloaded liver

The causes of an overloaded liver are diverse and primarily to be found in our fast-paced daily lives. For example, (chronic) stress is a serious factor. Furthermore, societal changes and our modern lifestyle have contributed to the fact that liver overload occurs more frequently today.

1. Lifestyle factors that can lead to liver overload: Regular alcohol consumption, regular medication use, nicotine, and an unhealthy diet with an excess of carbohydrates, fats, and sugar damage the organ.
2. Chronic diseases that can impair liver function: This includes diseases such as hepatitis, gallbladder disorders, or liver cirrhosis.
3. Genetic factors that can increase the risk of liver overload: e.g., hemochromatosis (iron metabolism disorder), Wilson's disease (copper metabolism disorder), or alpha-1 antitrypsin deficiency
4. Viral loads in the body that can affect the liver: e.g., infections or reactivations of the Epstein-Barr virus (EBV)

Typical symptoms of an overloaded liver

There are no pain receptors in the liver, which is why an overloaded liver develops insidiously without you feeling any pain. Symptoms of an overloaded liver can include, for example:

• Nausea
• Yellowing of the eyes
• High blood pressure
• Bloating or feeling of fullness
• Swelling between the eyebrows
• Extreme weight loss or
• Difficulty losing weight
• Fatigue and exhaustion
• Loss of appetite
• Impure, inflamed skin
• Headaches
• Brain fog
• Waking up at night
• Morning nausea
• Acne and impure skin
• Intolerances such as histamine intolerance or fructose malabsorption

• Irritability
• High sensitivity and emotionality
• Mood swings
• Sleep disorders
• Concentration problems
• Fatigue and exhaustion

If you feel pain in the upper abdomen (usually slightly to the right under the ribs), this can be an indication of a fatty liver. The pain arises because the liver has enlarged due to accumulated fat and is pressing on surrounding organs and tissue. Advanced fatty liver disease leads to scar tissue, which can result in further liver diseases such as liver cirrhosis and, in the worst case, liver failure. The good news is that the liver can regenerate even when a fatty liver is present. To achieve this, it is necessary to change your lifestyle, including your diet.

Diagnostics of histamine intolerance and liver dysfunction

To determine if you have liver overload or histamine intolerance, there are various diagnostic options. If liver overload is suspected, blood tests can provide information about liver values. In addition, an ultrasound or a liver biopsy can provide further insights. For histamine intolerance, an elimination diet can be carried out to test which foods trigger symptoms. Special breath tests or blood tests can also provide indications of histamine intolerance. However, in the case of unclear symptoms, it is important to see a doctor to obtain a correct diagnosis.

Important to know: Unfortunately, an overloaded liver only shows up in blood tests very late, so the symptoms and causes mentioned above should definitely be included in the diagnosis.

Top tips for strengthening the liver and supporting HNMT

There are several things you can do for your liver health. A balanced and low-histamine diet with natural, organic-quality foods is just the beginning. Further tips to effectively cleanse your liver are as follows:

• Plenty of green vegetables like broccoli, kale, lettuce, or chard strengthens liver function
• Protein-rich food supports the liver in burning fat
• Use high-quality fats like hemp or linseed oil. Omega-3 has an anti-inflammatory effect.
• Consume bitter substances for fat burning and liver detoxification (e.g., chicory, artichokes, radishes, Brussels sprouts, or wild herbs like dandelion)
• Antioxidants accelerate the excretion of toxins (e.g., garlic, apricots, red cabbage, or bell peppers)
• Drink sufficient still water (at least 2–3 liters a day) or unsweetened tea
• Plants like milk thistle for the regeneration and strengthening of liver cells
• Curcumin (found in turmeric) can protect the liver from toxins
• Spices like ginger can strengthen the immune system
• Nuts like Brazil nuts are rich in zinc and can support liver regeneration
• Zeolite to relieve the liver, kidneys, and pancreas

Would you like to easily integrate zeolite into your daily routine? Our ToxaFit was specially developed for people with histamine intolerance and other intolerances; it contains high-quality zeolite in practical capsule form, making it very easy to dose and incorporate into your everyday life.

• Avoid sugar, processed products, sugary drinks, alcohol, and coffee (caffeine) as much as possible
• Avoid medications and nicotine

• Perform a gut rehabilitation and liver cure (for at least 4 weeks)
• Exercise and sports like walking or cycling

Fasting, such as intermittent fasting, should be practiced with caution, as fasting cures like juice cleanses, in particular, can burden the body even more. The increased intake of fruit or fructose can increase fat storage in the liver and cause inflammation.

Conclusion: Liver health is crucial for the body's well-being

The liver plays a decisive role in the body's detoxification. It can be supported through targeted measures such as the consumption of specific herbs, spices, and plants like dandelion, turmeric, and milk thistle. Milk thistle is also available in the form of nutritional supplements and tea. Usually, an overloaded liver is only detectable in blood tests after a long phase of stress. Furthermore, pain is only perceived when a fatty liver already exists. This is reversible with the right treatment. Simple measures like liver compresses to improve blood circulation in the organ through warmth can support your liver in its regeneration.

Would you like to add something useful to your daily routine? Our LeberFit set practically combines the two products MetaFit and ToxaFit into one set.

MetaFit contains, among other things, milk thistle, dandelion, and coriander, as well as choline, which contributes to the maintenance of normal liver function. Together with ToxaFit, you get both products in one practical combination.

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