Histamine intolerance and mental health

In recent years, there has been a steady increase in mental illnesses, as shown by the Statista infographic "Sick Psyche: Record High in Absenteeism in 2020" from 2021. From 2000 to 2020, the number of sick days due to mental illnesses per 100 insured persons with DAK more than doubled. According to the RKI, more attention must therefore be paid to mental illnesses and their treatments. In this blog post, we want to focus on the connection between histamine intolerance and the human psyche.

What is a mental illness?

Mental illnesses are among the most common diseases, affecting mostly women and younger people up to 34 years of age. Mental illnesses are more prevalent in the lower socioeconomic class, while affective and psychotic disorders are more common in large cities. These include, in descending percentage:
  • Anxiety disorders
  • Unipolar depression
  • Disorders due to alcohol and drug use.

Causes of a mental illness

A mental illness usually does not have a single specific cause, but rather arises from a symbiosis of various causes. The following factors play a major role:

  • biological (e.g. developmental biological, genetic and neurochemical factors)
  • psychological (e.g. trauma and learning experiences)
  • social (e.g. education and caregivers)

Happy woman drinking tea in bed

However, the individual factors are more or less pronounced depending on the mental illness. Bipolar disorders and schizophrenias, for example, are caused by genetic or biological factors to 60-80%. For personality disorders and depression, the value is only just under 30%, as psychosocial factors play a greater role in this symptom complex.

According to the Statista Global Consumer Survey "When the head causes difficulties" from July/August 2021, the Corona pandemic also exacerbated existing mental problems in 35% of the 2,071 people surveyed in Germany. Stress and mood swings are the most common symptoms since Covid-19, closely followed by depressive phases and phases of sadness.

Histamine and psyche: Is there a connection?

Can psychological problems such as anxiety disorders and panic attacks arise from histamine intolerance and can existing psychological complaints be exacerbated by histaminosis? The answer is a clear YES. And there's a simple reason for that: Not only your gastrointestinal tract is affected by histaminosis, but your entire central nervous system is influenced by the neurotransmitter histamine, including your brain and your psyche. This is because histaminosis is a metabolic disease, i.e. a metabolic disorder. In addition to common symptoms such as migraines, sleep and concentration disorders, the following psychological symptoms of histamine intolerance are therefore also possible:

  • Anxiety and panic attacks
  • Mood swings
  • Concentration problems
  • Nervous agitation
  • Fatigue
  • Aggression
  • Irritability
Various scientific studies have also shown that
a person's emotional state not only has a significant influence on the strength of an allergic reaction, but also of a histamine surge.

ATTENTION: Therapy with antidepressants is counterproductive in the presence of histamine intolerance, as the medication does not combat the causes, but can additionally restrict DAO function and cause histamine release. If medication is pending, be sure to inform your treating doctor/psychiatrist about your histaminosis.

Medical consultation

Anxiety and panic due to histamine: The brain is the key

The human brain not only receives an extremely large number of signals every day, but also has to process them. The stimuli are regulated by the histaminergic system, which belongs to the autonomic nervous system. This process is also called homeostasis and describes self-regulation, in which histamine is also involved.

In stressful situations, for example, the release of histamine from mast cells can lead to itching. Intolerance symptoms, in turn, lead to an increase in the activity of mast cells in the brain, which leads to increased histamine release and can trigger psychological complaints such as panic or anxiety.

Histamine is formed in the brain in the hypothalamus, which is located in the diencephalon. It therefore becomes clear that there is a connection between mental illnesses and the mast cells that release histamine. The brain often reacts to continuous histamine release as an immune response with inflammatory reactions, which in turn trigger anxiety or emotional distress. Mast cells influence neuronal systems and cause both a change in behavior and in hormone status.

Conversely, this means for you: If you suffer from a mental illness in which the mast cells are very active, this will most likely have a negative effect on an existing histaminosis.

ATTENTION: Caution is also advised when taking histidine. This amino acid is broken down into histamine in the body and can affect the psyche.


Especially with a histamine problem, a balanced supply of important micronutrients is useful. Our BalanceFit combines carefully selected vitamins, minerals and plant substances. Vitamin B6 contributes to the normal functioning of the nervous system and to normal psychological function. In addition, folate and vitamin B12 contribute to the reduction of tiredness and fatigue. BalanceFit is vegan and suitable for a low-histamine, low-fructose, gluten-free and lactose-free diet.

BalanceFit
5,0 (33)
BalanceFit
Micronutrient Complex for your daily well-being.
with vitamins B6, B12, folic acid, zinc & selenium
with quercetin & OPC from grape seeds
contributes to the normal function of the immune system and normal energy metabolism*
laboratory-tested & free from unnecessary additives
33,46 €
656,98 € / kg

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Histamine intolerance symptoms and psyche — our conclusion

Histamine intolerance and psyche condition and influence each other. Therefore, it is essential that you pay attention to your mental health and reduce stress. Targeted breathing exercises or meditations can positively influence your psyche by calming the mast cells in the brain through stress reduction.

Sources

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